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Yes, you 100% need a PCT when running a stack with YK-11 and other aggressive compounds. YK-11 does create a suppressive effect on the Hypothalamic Pituitary Testicular Axis (HPTA), mk-677 and rad-140. Ligandrol ' can cause testosterone suppression (and is the most suppressive of the SARMs sold). As a result, you will need to PCT after using, primeval labs cardarine review. This means that users can experience a wealth of muscle building effects without all the associated androgenic side effects, best lgd 4033 powder. RAD is powerful enough to limit the effect of testosterone on the prostate and other unwanted areas. Look into this ingredient and the science behind it, and you'll quickly learn why it's a great and effective alternative. If you're dead set on taking SARMs anyway, it's crucial to stock up on both Rebirth (post cycle therapy) and Defend (organ support), sarms lgd 4033 ligandrol. 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